Deficit

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deficit.jpg
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Deficit

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Regular price $49.95/bottle. 

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Deficit


  • Burn fat fast.
  • Clean energy and focus. 
  • Appetite and craving control. 
  • No proprietary blends. 

Deficit builds on the NSI pledge of combining research-backed ingredients at clinical dosages shown to be effective for achieving results.

When combined with a daily calorie deficit and regular exercise routine, Deficit helps accelerate results and provide support for a strong metabolism, suppressed appetite, and improved focus and mental alertness.  


DIRECTIONS

Take 1 serving (2 capsules) twice daily on an empty stomach. Take the first serving in the morning and second serving mid-afternoon. Do not exceed 2 servings (4 capsules) in a 24-hour period. Read entire label before use including warning.


THE SCIENCE BEHIND DEFICIT

GREEN COFEE BEAN

Effective Dosage: 200mg CGA

Caffeine isn’t the only biologically active substance in coffee – it also contains phenolic compounds (polyphenols) including chlorogenic acids (CGA). CGA is found in many fruits and vegetables, but green coffee bean contains more than any other plant source. 

Chlorogenic acid is able to reduce insulin and glucose spikes following a meal without affecting overall levels of insulin or glucose significantly. 

Longer term intake can reduce carbohydrate uptake, with the most promising result being 6.9% reduced glucose absorption in the intestines. 

SYNEPHRINE

Effective Dosage: 20mg

Much of the science and facts of ephedrine extend to synephrine, except both efficacy and side-effects are reduced due to lesser potency.

A single dose of 50mg  synephrine, when measured over the next 75 minutes in otherwise healthy subjects in a rested state, has been noted to increase by 65kcal (a 35kcal increase from baseline whereas placebo was decreased 30kcal) and this was without any influence on blood pressure or cognition.

Synephrine can increase the metabolic rate via increasing lipolysis and basal metabolic rate. These effects are independent of diet for the most part, and can exert a passive increase in basal metabolic rate to produce weight loss over an extended period of time.
Synephrine has been implicated in increasing the thermic effect of food, but one study noted this effect only in women.

FUCOXANTHIN

Effective Dosage: 3mg

Fucoxanthin, via its metabolites, seems to be stored in fat cells for a prolonged period of time and can induce fat loss while inhibiting fat cell differentiation and proliferation. It appears to be a promising non-stimulatory fat loss agent but requires time to work (5-16 weeks).

It also possesses other health benefits, such as correcting abnormalities in glucose metabolism in muscle tissue which can help diabetics and might reduce cholesterol levels and triglycerides by currently unverified mechanisms. Reductions in blood pressure and reductions in both liver fat stores and liver enzyme values have been noted with Fucoxanthin supplementation in humans.

YOHIMBINE

Effective Dosage: 4-5mg

Yohimbine is the alkaloid extract from the plant yohimbe. Yohimbine works by increasing adrenaline levels in the body, as well as inhibiting a regulatory process in fat cells, which normally suppresses fat burning. The effects of yohimbine are partially negated by food intake, which is why it is often taken in a fasted state.

Antagonism (Inactivation) of the Alpha-2-Adrenergic receptors preserves fat burning effects mediated via other mechanisms, a negation of a suppressive effect that ultimately results in more lipolysis (fat burning)

RHODIOLA ROSEA

Effective Dosage: 250mg

Rhodiola rosea is an herb which has traditional usage as an anti-fatigue/stress agent and adaptogen compound. 

Rhodiola may possibly reduce the ingestion or preference for certain food types (fats or sweets) or can reduce appetite during certain periods of time where emotional eating would increase. Specifically, rhodiola rosea has been shown to either reduce or eliminate stress-induced binge eating in overweight females. 

MAGNOLIA BARK

Effective Dosage: 250mg

Shown to reduce the cravings from food induced by stress in a sample of obese but otherwise healthy women. The dose shown to be effective in studies was 250mg taken 2-3 times daily.

COLEUS FORSKOHLI

Effective Dosage: 100mg

Coleus Forskohlii is an ancient Indian herb that is commonly used currently as a fat burning compound through its main compound Forskolin. Forskolin is commonly used as a research tool to increase cAMP. When cAMP increases, a wide range of signaling properties occurs.

The main supplementation use of Forskolin is to increase cAMP in fat cells, which increases the rate of fat loss and can make other fat burners better at fat burning.

In general, increasing cAMP can in part mimic caloric restriction and exercise as cAMP is a signal of energy deprivation or energy usage.

5-HYDROXYTRYPTOPHAN [5-HTP]

Effective Dosage: 50mg

5-HTP is a supplement that is known to increase satiety (rather than reduce appetite) and should be co-ingested with food. It has only currently been tested in overweight and obese individuals, but appears to reliably reduce food intake to around 60% of baseline values (placebo groups tend to hit 80%).

L–THEANINE

Effective Dosage: 100mg 

A combination of L-theanine with caffeine is noted to be synergistic in promoting cognition and attention/focus. L-theanine supplementation may help take the edge off stimulant-based products. 

CAFFEINE

Effective Dosage: 200mg 

Caffeine’s main mechanism concerns antagonizing adenosine receptors. Adenosine causes sedation and relaxation when it acts upon its receptors, located in the brain. Caffeine prevents this action and causes alertness and wakefulness. This inhibition of adenosine can influence the dopamine, serotonin, acetylcholine, and adrenaline systems.

30 minutes after an oral dose of 4mg/kg caffeine (in obese women), a metabolic spike was seen in all subjects but to a widely varied degree; this spike is able to reduce body weight when in conjunction with a low-calorie regimen in all subjects though.

Despite the high variance seen, average increases seem to be around 34kJ/m2/hour, which translates to 8.1 calories per hour for every meter of body surface area a person has. The standard 'average' for adult humans of normal weight is 1.73m2, which translates into 14kcal per hour. Some studies note higher values (32.4kcal/h) with higher dosages of caffeine (400mg).